Photodynamic therapy
Information
- Drug Name
- Photodynamic therapy
- Description
- Entry(CIViC)
CIViC
[No Data.]
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| Inhibition of heme oxygenase-1 increases responsiv... | HMOX1 | HMOX1 UNDEREXPRESSION | Sensitivity | true | MMMP | detail |
| Dominant negative experiments | BIRC5 | BIRC5 EXPRESSION | Resitance or Non-Reponse | true | MMMP | detail |
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03467789 | Active, not recruiting | Phase 1 | Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma | October 1, 2018 | September 1, 2024 |
| NCT03678350 | Active, not recruiting | Phase 1 | Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery | September 17, 2021 | November 13, 2025 |
| NCT00077012 | Completed | Phase 1/Phase 2 | Dose Escalation Study With QLT0074 for Benign Prostatic Hyperplasia | March 2003 | May 2005 |
| NCT00083785 | Completed | Phase 2 | Study of the Litx™ System Combined With Chemotherapy in Patients With Colorectal Liver Metastases | May 2004 | |
| NCT00122876 | Completed | Phase 1/Phase 2 | Tumor Ablation With Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC) | April 2005 | October 2006 |
| NCT00155337 | Completed | Phase 4 | Photodynamic Therapy for Oral Leukoplakia and Erythroleukoplakia | August 2004 | December 2007 |
| NCT00206895 | Completed | N/A | Photodynamic Therapy of Acne Vulgaris - a Randomized Blinded Controlled Study | November 2004 | |
| NCT00217087 | Completed | Phase 2 | Endoscopic Therapy of Early Cancer in Barretts Esophagus | September 2005 | June 2012 |
| NCT00308854 | Completed | Phase 3 | Photodynamic Therapy With PD P 506 A Compared With Placebo-PDT for the Treatment of AK | March 2006 | December 2007 |
| NCT00308867 | Completed | Phase 3 | PD P 506 A-PDT Versus Placebo-PDT and Cryosurgery for the Treatment of AK | March 2006 | November 2007 |
| NCT03142776 | Completed | N/A | Nonsurgical Periodontal Treatment Associated or Not With Systemic Antibiotics and Photodynamic Therapy | March 2014 | August 2015 |
| NCT03308019 | Completed | N/A | Adjunct Photodynamic Therapy in Chronic Periodontitis Among Cigarette-smokers. | February 16, 2016 | September 16, 2017 |
| NCT00068068 | Completed | Phase 2 | Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases | October 2003 | |
| NCT02049008 | Completed | Phase 4 | Treatment of Aggressive Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy | January 2013 | March 2014 |
| NCT03638622 | Completed | Phase 1/Phase 2 | Low-cost Enabling Technology for Image-guided Photodynamic Therapy (PDT) of Oral Cancer Cancer. | March 10, 2017 | October 12, 2020 |
| NCT02416531 | Completed | N/A | Vulvar Lichen Sclerosus: Comparison Between Clobetasol Propionate, Photodynamic Therapy and Low-Intensity Laser | January 2015 | October 2017 |
| NCT02642900 | Completed | Phase 4 | Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers | July 2009 | July 2011 |
| NCT03591484 | Completed | N/A | Treatment of Halitosis With Photodynamic Therapy in Older Patients | June 1, 2019 | August 1, 2021 |
| NCT02734784 | Completed | Phase 4 | Treatment of Chronic Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy | February 2014 | February 2016 |
| NCT02848482 | Completed | Phase 3 | Anti-infective Effect of Non-surgical Treatment With and Without Photodynamic Therapy on Initial Peri-implantitis | May 1, 2017 | May 1, 2019 |
| NCT03033225 | Completed | Phase 2 | Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study | December 6, 2016 | September 20, 2023 |
| NCT03039244 | Completed | N/A | Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers | September 1, 2014 | September 1, 2017 |
| NCT03498404 | Completed | Phase 4 | Evaluation of Antimicrobial Photodynamic Therapy in Multiple Applications as a Coadjuvant in the Surgical Therapy of Access to Scaling | April 7, 2018 | April 7, 2018 |
| NCT03281811 | Completed | Early Phase 1 | Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides | November 13, 2017 | August 12, 2020 |
| NCT00395187 | Completed | N/A | A Small Clinical Study: Photodynamic Therapy to Treat Hidradenitis Suppurativa | October 2006 | September 2007 |
| NCT00432224 | Completed | N/A | Treatment of Actinic Keratoses With Photodynamic Therapy Using Sunlight Versus Red Light | May 2006 | February 2007 |
| NCT00453336 | Completed | Phase 2 | Photodynamic Therapy With Porfimer Sodium in Treating Patients With Precancerous Lesions, Cancer, or Other Disease of the Aerodigestive Tract | June 2003 | May 2010 |
| NCT00470496 | Completed | Phase 1 | Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer | October 19, 2006 | August 30, 2018 |
| NCT00558688 | Completed | N/A | A Photodynamic Therapy for Treatment of Actinic Keratoses | August 2007 | August 2009 |
| NCT00587600 | Completed | Phase 2/Phase 3 | Biomarkers in Phototherapy of Barrett's Esophagus | December 2002 | April 21, 2017 |
| NCT00784108 | Completed | Phase 1 | Optimizing Photodynamic Therapy of Cutaneous Neoplastic Diseases Via Structured Illumination and Real-time Dosimetry. | October 2008 | September 2012 |
| NCT00849992 | Completed | Phase 4 | Treatment Study for Actinic Cheilitis Comparing Imiquimod 5% and Photodynamic Therapy | March 2009 | November 2013 |
| NCT00869635 | Completed | Phase 3 | S-1 and Photodynamic Therapy in Cholangiocarcinoma | February 2009 | August 2013 |
| NCT00985829 | Completed | Phase 1 | Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma | January 2008 | March 2009 |
| NCT00988455 | Completed | Phase 1/Phase 2 | Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma With 6 Months Follow-up | January 2008 | August 2009 |
| NCT01015898 | Completed | Phase 1 | Short Term Effects of Photodynamic Therapy in Basal Cell Carcinoma | January 2008 | September 2008 |
| NCT01034501 | Completed | Phase 4 | Adjunctive Photodynamic Therapy in Treatment of Chronic Periodontitis | February 2010 | September 2013 |
| NCT04976673 | Completed | Phase 2 | Comparison of Clinical Efficiency of Photodynamic Therapy and Topical Corticosteroid in Treatment of Oral Lichen Planus | December 10, 2020 | May 22, 2021 |
| NCT01245946 | Completed | Phase 2 | Photodynamic Therapy Compared to Adapalene 0.1% Gel Plus Doxycycline in the Treatment of Acne Vulgaris | October 2010 | May 2011 |
| NCT01292668 | Completed | Phase 1 | Photodynamic Therapy Using Methyl-5-Aminolevulinate Hydrochloride Cream in Determining Pain Threshold in Patients With Skin Cancer | March 2011 | September 2014 |
| NCT04618276 | Completed | N/A | Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-II) | January 15, 2021 | June 24, 2021 |
| NCT04429139 | Completed | N/A | Photodynamic Therapy With Visudyne for Human Retinoblastoma: A Preliminary Study | February 1, 2011 | May 30, 2020 |
| NCT04301999 | Completed | N/A | Clinical Effect and Safety of PDT and RFA for Unresectable EHCC | March 1, 2020 | August 27, 2021 |
| NCT01668823 | Completed | Phase 1 | Photodynamic Therapy in Treating Patients With Lung Cancer | February 2004 | June 2014 |
| NCT03960983 | Completed | N/A | Evaluation of the Treatment of Halitosis With Photodynamic Therapy in Older Patients With Complete Denture | June 1, 2019 | August 1, 2021 |
| NCT03864718 | Completed | Photodynamic Therapy in Anal Fistula | January 2016 | December 2018 | |
| NCT01770132 | Completed | Phase 1 | Ultrasound-Guided Photodynamic Therapy With Photofrin & Gemcitabine for Patients With Locally Advanced Pancreatic Cancer | April 19, 2013 | October 28, 2018 |
| NCT01800838 | Completed | Phase 1 | Silicon Phthalocyanine 4 and Photodynamic Therapy in Stage IA-IIA Cutaneous T-Cell Non-Hodgkin Lymphoma | April 2013 | May 2015 |
| NCT01854684 | Completed | Phase 1 | Photodynamic Therapy During Surgery in Treating Patients With Non-small Cell Lung Cancer That Can Be Removed by Surgery | February 21, 2014 | September 4, 2018 |
| NCT05820750 | Enrolling by invitation | N/A | Clinical and Radiographic Evaluation of Photodynamic Therapy for Root Canal Treatment of Primary Molars | December 1, 2022 | May 1, 2024 |
| NCT03576105 | Enrolling by invitation | N/A | Evaluation of Photodynamic Therapy in Pericoronitis | December 1, 2019 | June 15, 2024 |
| NCT06381154 | Not yet recruiting | Phase 2 | Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer | June 30, 2024 | July 4, 2029 |
| NCT05386056 | Not yet recruiting | Phase 2 | Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell Carcinoma | December 1, 2022 | June 30, 2024 |
| NCT06331442 | Not yet recruiting | N/A | The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients | May 2024 | November 2024 |
| NCT06437288 | Not yet recruiting | Phase 2 | Hematoporphyrin Photodynamic Therapy for Esophageal Cancer | May 31, 2024 | December 1, 2027 |
| NCT04429308 | Not yet recruiting | Phase 2 | PDT vs Peels for Treatment of Actinic Keratoses | January 2025 | December 2025 |
| NCT02153229 | Recruiting | Phase 2 | Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma | May 2014 | December 2024 |
| NCT06305533 | Recruiting | N/A | Efficacy of Photodynamic Therapy and LASER Disinfection in Periodontal Therapy for Treatment of Periodontitis | March 1, 2024 | October 2024 |
| NCT05676801 | Recruiting | Early Phase 1 | Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-III) | February 4, 2023 | December 31, 2023 |
| NCT06445699 | Recruiting | N/A | Photodynamic Therapy With Hydrogel Dressing for Chronic Wounds | January 1, 2023 | June 2024 |
| NCT06307548 | Recruiting | Phase 1/Phase 2 | Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer | June 1, 2024 | June 1, 2027 |
| NCT04836429 | Suspended | Phase 1 | Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease | March 10, 2022 | March 17, 2025 |
| NCT01859169 | Suspended | Safety and Efficiency of Photodynamic Therapy for Blie Duct Carcinoma | June 2013 | June 2016 | |
| NCT01872104 | Suspended | Phase 2/Phase 3 | Safety and Efficiency of Photodynamic Therapy for Rectal Cancer | August 2013 | August 2016 |
| NCT00005808 | Terminated | Phase 1 | Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia | December 2000 | |
| NCT03564054 | Terminated | N/A | Trial of Photodynamic Therapy Versus Argon Plasma Coagulation for Lung Cancer With Endobronchial Obstruction | October 11, 2018 | September 30, 2019 |
| NCT03573076 | Terminated | Phase 4 | Treatment of Photodamaged Skin of the décolleté | September 10, 2018 | December 18, 2018 |
| NCT02068157 | Terminated | Phase 2 | Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer | April 1, 2014 | November 4, 2016 |
| NCT01538901 | Terminated | Phase 4 | Imiquimod Versus Photodynamic Therapy of Actinic Keratoses in Organ Transplant Recipients | September 2012 | September 2014 |
| NCT00005067 | Terminated | Phase 1 | Photodynamic Therapy With Lutetium Texaphyrin in Treating Patients With Locally Recurrent Prostate Cancer | February 2000 | |
| NCT01203878 | Terminated | Phase 4 | Treatment of Actinic Keratoses of the Face With Imiquimod 3.75% Cream Followed by Photodynamic Therapy | September 2010 | November 2011 |
| NCT00571558 | Terminated | Phase 1 | Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Oral Leukoplakia | March 2008 | November 2010 |
| NCT00540735 | Terminated | Phase 3 | Efficiency Evaluation of Photodynamic Therapy With Photofrin® on Unresectable Type III or IV Cholangiocarcinomas | April 2008 | November 2009 |
| NCT00472706 | Terminated | Phase 4 | Trial of Excision Versus Photodynamic Therapy in the Treatment of Bowen's Disease | May 2007 | February 2010 |
| NCT03090412 | Terminated | Phase 2 | Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer | March 7, 2018 | August 6, 2021 |
| NCT03656419 | Unknown status | N/A | Photodynamic Therapy With Red Leds in Microorganisms Related to Halitosis | January 2, 2018 | December 10, 2018 |
| NCT00840359 | Unknown status | Phase 2 | Study of the Efficacy of Daylight Activated Photodynamic Therapy in the Treatment of Cutaneous Leishmaniasis | September 2009 | December 2012 |
| NCT03770819 | Unknown status | N/A | PDT As An Adjunct To SRP In The Management of Chronic Periodontitis | March 2019 | June 2019 |
| NCT01755013 | Unknown status | Phase 2/Phase 3 | Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma | February 2012 | March 22, 2018 |
| NCT01524146 | Unknown status | Photodynamic Therapy (PDT) Cholangiocarcinoma Registry | November 2011 | December 30, 2018 | |
| NCT01481155 | Unknown status | N/A | Comparative Study of Photodynamic Therapy vs. CO2 Laser Therapy in Treatment of Actinic Keratoses | March 2011 | |
| NCT04213638 | Unknown status | N/A | Trial of Single Microneedle Radiofrequency for Moderate-to-Severe Acne Vulgaris | November 15, 2019 | November 2020 |
| NCT00365521 | Unknown status | N/A | Prophylactic Photodynamic Therapy to Organ Transplant Patients | April 2009 | |
| NCT05003492 | Unknown status | Phase 1/Phase 2 | Utilizing the Crosstalk Among Aerosolized Phenformin , Methylene Blue, Photodynamic Therapy , Zinc and Potassium for Treating Severe COVID-19 Infection and Its Inflammatory Complication | September 2021 | November 2021 |
| NCT01043016 | Unknown status | Phase 1 | Safety Study of Photodynamic Therapy Using Photocyanine Injection in Treating Patients With Malignant Tumors | March 2009 | April 2010 |
| NCT03079141 | Unknown status | Phase 4 | Photodynamic Therapy Versus Eplerenone: Treatment Trial for Chronic Central Serous Chorioretinopathy | February 20, 2017 | August 2021 |
| NCT02725073 | Unknown status | Phase 2 | Photodynamic Therapy in Locally Advanced Hilar Cholangiocarcinoma | January 2016 | December 2017 |
| NCT01630863 | Unknown status | N/A | The Safe Effective Light Dose of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy | June 2012 | March 2015 |
| NCT03960125 | Withdrawn | Early Phase 1 | Photodynamic Therapy and Microvesicles | March 29, 2021 | September 2022 |
| NCT00253617 | Withdrawn | Phase 3 | Stent Placement With or Without Photodynamic Therapy Using Porfimer Sodium as Palliative Treatment in Treating Patients With Stage III or Stage IV Cholangiocarcinoma That Cannot Be Removed By Surgery | ||
| NCT02106559 | Withdrawn | N/A | Photodynamic Therapy During Surgery in Treating Patients With Pleural Malignancy | September 4, 2014 | January 29, 2016 |
| NCT00930189 | Withdrawn | Phase 2/Phase 3 | Comparative Study With Photodynamic Therapy And Triamcinolone Versus Photodynamic Therapy, Triamcinolone And Ranibizumab In Patients With Subfoveal Choroidal Neovascularization | April 2006 | September 2006 |
| NCT01718223 | Withdrawn | N/A | Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent Oral Cavity or Oropharyngeal Cancer | December 2013 | August 2014 |